THE EXTRACELLULAR MATRIX PROVIDES DIRECTIONAL CUES FOR NEURONAL MIGRATION DURING CEREBELLAR DEVELOPMENT


Positivity bounds on Higgs-Portal dark matter

Abstract We consider the Dongs positivity bounds for WIMP scalar dark matter with effective Higgs-portal couplings up to dimension-8 operators.Taking the superposed states for Standard Model Higgs and scalar dark matter, we show that the part of the parameter space for the effective couplings, otherwise unconstrained by phenomenological bounds, is

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Harvesting strategies as evidence for 4000 years of camas (Camassia quamash) management in the North American Columbia Plateau

One of the greatest archaeological enigmas is in understanding the role of decision-making, intentionality and interventions in plant life cycles by foraging peoples in plate transitions to and from low-level food production practices.We bring together archaeological, palaeoclimatological and botanical data to explore relationships over the past 40

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Virtual screening of combinatorial library of novel benzenesulfonamides on mycobacterial carbonic anhydrase II

Combinatorial library of novel benzenesulfonamides was docked (Schrodinger Glide) into mycobacterial carbonic anhydrase (mtCA II) and human (hCA II) isoforms with an aim to find drug candidates with selective activity Hydrating Serum on mtCA II.The predicted selectivity was calculated based on optimized MM-GBSA free energies for ligand enzyme inter

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